HbA2 Trilevel Controls (Lyophilized)

Detection of β-Thalassemia Minor Trait

The normal adult blood level of HbA2 ranges from about 1.4% - 3.2%. However in cases of β-thalassemia, where there is a deficit in production of β - chains, the levels of HbA2 can be elevated above 3.5%. Hence the measurement of an elevated HbA2 blood level has become the single most important diagnostic test to identify carriers of the β-thalassemia trait.

The extendSURE™ control kitset comprises a set of trilevel lyophilized controls with reconstitution fluid and cover the patho-physiological range. They have an unopened shelf life of 3 years stored at 2°C - 8°C with open vial stability of 4 weeks. They are suitable for the main methods used to quantify HbA2 including Cellulose Acetate Electrophoresis with elution of the separated bands, Anion-exchange Micro Column Chromatography, Automated High Performance Liquid Chromatography and Capillary Electrophoresis.